Inorganic Chemistry: Development of MRI contrast agents; NMR properties of aqueous solutions of paramagnetic ions; EPR spectroscopy of transition
metal complexes; fundamental aspects of coupled group/multielectron
transfer reactions in solution.
Our research interests are in medicinal inorganic and physical inorganic chemistry and are particularly
focused on the development
of paramagnetic transition metal complexes with potential uses as MRI contrast
agents. These studies involve the synthesis and detailed NMR relaxivity
characterization of small Mn(II), Fe(III), Cu(II), and Cr(III) complexes. We
are also interested in the general mechanisms of atom transfer reactions in
solution and are studying a number of inorganic atom transfer systems in detail
to define the dependence of the reaction kinetics on molecular properties.
Selected Publications
- "Spectroscopic and Crystallographic Characterization of
(s2-terpyridyl) Re(CO)3Cl. 2D-NMR Evidence for a Linkage Isomerization Reaction" E. R. Civitello, P. S. Dragovich, T. Karpishin, S. G. Novick, G. Bierach, J. F. O'Connell, T. D. Westmoreland Inorg. Chem. 32, 237-241 (1993).
- "New Ruthenium(IV) Complexes via Oxidative Cp*-Ru Bond Rupture and Methyl Activation in Decamethylruthenocene" S. P. Deraniyagala and T. D. Westmoreland,
Organometallics 14, 1239-1241 (1995).
- "Synthesis and Characterization of Tp*MoOX2(X=F, Cl, Br; Tp*=hydro-tris-(3,5-dimethylpyrazol-1-yl)borate)" N. S. Nipales and T. D. Westmoreland Inorg. Chem. 34, 3374-3377 (1995).
- "Hydride Abstraction Reactivity of Haloruthenoceniums and Haloosmoceniums"
A. N. Xu, D. B. Studebaker, and T. D. Westmoreland Organometallics 15, 4888-4890 (1996).
- "Coupled Two-Electron/Halide Transfer Reactions of Ruthenoceniums and Osmoceniums"
T. M. Shea, S. P. Deraniyagala, D. B. Studebaker, and T. D. Westmoreland Inorg. Chem. 35, 7699-7703 (1996).
- "Electronic Structural Contributions to g Values and Molybdenum Hyperfine Coupling Constants in Oxyhalide Anions of Molybdenum(V)" C. Balagopalakrishna, J. T. Kimbrough, and T. D. Westmoreland Inorg. Chem. 35, 7758-7768 (1996).
- "Correlation of EPR Parameters with Electronic Structure in the Homologous Series of Low Symmetry Complexes Tp*MoOX2 (Tp*=hydro-tris-(3,5-dimethylpyrazol-1-yl)borate); X=F, Cl, Br)" N. S. Nipales and T. D. Westmoreland Inorg. Chem. 36, 756-757 (1997).
- "A New Irreversibly Inhibited Form of Xanthine Oxidase From Ethylisonitrile" S. A. Holmer, C. L. Houlton, and T. D. Westmoreland J. Inorg. Biochem. 66, 63-65 (1997).
- "Density Functional Calculations of g Values and Molybdenum Hyperfine Coupling Constants for a Series of Molybdenum (V) Oxyhalide Anions" J. Swann and T. D. Westmoreland Inorg. Chem., 36, 5348-5357 (1997).
- "Electronic Effects on the Rates of Coupled Two-Electron/Halide Self-Exchange Reactions of Substituted Ruthenocenes" T. M. Shea and T. D. Westmoreland Inorg. Chem., 39, 1573-1577 (2000).
- Symmetry Control of Chemical Reactions: Applications to the Berry
Pseudorotation of Five-Coordinate Transition Metal Complexes" T. D..
Westmoreland Inorg. Chem. Acta, submitted (2007).
Education
- B.S. 1980 Massachusetts Institute of Technology
- Ph.D. 1985 University of North Carolina at Chapel Hill
[Chemistry]
[Wesleyan]
Last updated: August 10, 2007 (RNCB)
